Systematic Review of Human Postmortem Immunohistochemical Studies and Bioinformatics Analyses Unveil the Complexity of Astrocyte Reaction in Alzheimer’s Disease

We performed a systematic review of the neuropathological literature followed by bioinformatics analyses to reveal the complexity of AD reactive astrogliosis.

Dependencies

To run our code, please install the R programming language and statistical computing environment (version 4.1.0). Additional required packages are specified in each script.

ayushnoori

Documentation

To read our documented code, please visit www.serranopozolab.org/astrocyte-review.

Code Availability

Our full codebase is available for download on GitHub.

Corrections

If you see mistakes or want to suggest changes, please create an issue on the source repository.

Website developed by Ayush Noori in the Serrano-Pozo Lab at Massachusetts General Hospital and Harvard Medical School. Code released under the GNU General Public License v3.0.